Clinical Trial Finder

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Clinical trials are listed below.

  • Anti-InfectiveEnrolling Location: Australia

    A comparative assessment of the clinical impact , protocol number ACTRN12607000349448

    This study is designed to provide vitally needed information on the clinical implications of being infected by a clonal strain of P. aeruginosa and the risk factors for the acquisition of a clonal strain. This new information will provide a rational basis for the need for changes to infection control policies and better outcome predictors for patients infected with clonal strains of P. aeruginosa.

    • Age:

      2-75 years

    • Mutation(s):

      Not specified

    • FEV1% Predicted:

      Not Specified

    • Number of Visits:

      Not specified

    • Length of Participation:

      Not Specified

    Contact us about this clinical Trial >
  • BehavioralEnrolling Location: Australia

    Engaging and re-connecting 'at-risk' children with chronic respiratory illness. , protocol number ACTRN12607000515493

    Children with chronic illness sometimes feel disconnected and lonely. In this study we will evaluate the use of a psycho-social intervention program for 'at-risk' children (ie. child with chronic illness, low socio-economic groups) to improve their sense of well-being, adherence to therapies and health outcomes.

    • Age:

      10-15 years

    • Mutation(s):

      Not specified

    • FEV1% Predicted:

      Not Specified

    • Number of Visits:

      Not specified

    • Length of Participation:

      Not Specified

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  • OtherEnrolling Location: Australia

    Effect of a targetted exercise program versus current exercise practice on function, activity and participation of young people with cystic fibrosis: a randomised, controlled trial , protocol number ACTRN12607000612415

    Exercise is a vital component of the physiotherapy management for young people with cystic fibrosis (CF). The overall aim of this research is to strengthen knowledge about best practice exercise programs for this population. This study compares effects of two exercise programs (the current exercise practice versus a novel targeted exercise program). Ultimately, it is expected that with improved exercise programs, young people with CF may have improved body structure and function, and activity and participation levels, leading to enhanced quality of life.

    • Age:

      18-70 years

    • Mutation(s):

      Not specified

    • FEV1% Predicted:

      40% predicted or above

    • Number of Visits:

      Not specified

    • Length of Participation:

      Not Specified

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  • BehavioralNot yet recruiting Location: Australia

    Stretching in cystic fibrosis: does it improve the quality of life and measures of kung function. , protocol number ACTRN12608000484347

    Stretching in cystic fibrosis: does it improve the quality of life and measures of kung function.

    • Age:

      18-70 years

    • Mutation(s):

      Not specified

    • FEV1% Predicted:

      >40% or above

    • Number of Visits:

      Not specified

    • Length of Participation:

      Not Specified

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  • ObservationalEnrolling Location: Multiple US sites

    Rare Mutation Cell Collection (RARE) , protocol number NCT 03161808 NCT 03161808

    This study is taking place at multiple care centres across the US. Researchers will collect and make available for study cells from people with rare CFTR mutations.

    • Age:

      2 years and older

    • Mutation(s):

      No mutation requirement

    • FEV1% Predicted:

      40-90%

    • Number of Visits:

      8

    • Length of Participation:

      30 days

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  • Restore CFTR FunctionEnrolling Location: Australia

    A Study to Evaluate the Efficacy and Safety of Lumacaftor in Combination With Ivacaftor in Subjects With CF, Homozygous for the F508del-CFTR Mutation , protocol number VX14-809-109 NCT02514473

    A Phase 3, Double Blind, Placebo Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Lumacaftor in Combination With Ivacaftor in Subjects Aged 6 Through 11 Years With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation

    • Age:

      6-11 years

    • Mutation(s):

      homozygous for the F508del CFTR mutation

    • FEV1% Predicted:

      ppFEV1 of ≥70 p

    • Number of Visits:

      Not specified

    • Length of Participation:

      Not Specified

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  • Restore CFTR FunctionEnrolling Location: Australia

    Study of GLPG1837 in Subjects With Cystic Fibrosis (G551D Mutation) (SAPHIRA1) , protocol number NCT02707562

    A Phase IIa, Open-label Study of Multiple Doses of GLPG1837 in Subjects With Cystic Fibrosis and the G551D Mutation

    • Age:

      >18 years

    • Mutation(s):

      G551D

    • FEV1% Predicted:

      Pre- or post-bronchodilator FEV1 ≥ 40% of predicted normal

    • Number of Visits:

      Not specified

    • Length of Participation:

      Not Specified

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  • OtherEnrolling Location: Australia

    The Alfred Step Test Exercise Protocols (A-STEP and A-STEPmax): Developed for Adults With Cystic Fibrosis (A-STEP/max) , protocol number NCT02717650

    Feasibility and Validation of the Alfred Step Test Exercise Protocols (A-STEP and A-STEPmax): Developed to Assess Exercise Tolerance and Determine Maximum Oxygen Uptake in Adults With Cystic Fibrosis Across the Disease Spectrum

    • Age:

      >18 years

    • Mutation(s):

      Not specified

    • FEV1% Predicted:

      FEV1 greater than 20%

    • Number of Visits:

      Not specified

    • Length of Participation:

      Not Specified

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  • Mucociliary ClearanceEnrolling Location: Multiple care centres across the US

    Phase 1Bstudy of inhaled AZD5634 in adults with CF , protocol number NCT02950805

    This study is taking place at multiple care centres accross the US. It will look at the safety and tolerability of the inhaled drug AZD5634 in adults with CF.

    • Age:

      18 - 60 years

    • Mutation(s):

      No mutation requirement

    • FEV1% Predicted:

      40% or greater

    • Number of Visits:

      4

    • Length of Participation:

      4 months

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  • OtherEnrolling Location: Multicentre

    Saline Hypertonic in pre-schoolers + CT (SHIP-CT) , protocol number NCT02950883

    The purpose of this study is to assess whether inhalation of 7% hypertonic saline (HS) twice daily for 48 weeks reduces structural lung disease as assessed by computed tomography (CT) in comparison with inhalation of 0.9% isotonic saline (IS) in preschool children (ages 3 to 6) with cystic fibrosis.

    • Age:

      3-5 years

    • Mutation(s):

      A documented genotype with two disease-causing mutations in the CFTR gene

    • FEV1% Predicted:

      Not Specified

    • Number of Visits:

      Not specified

    • Length of Participation:

      Not Specified

    Contact us about this clinical Trial >
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